Manju Hingorani, associate professor of molecular biology and biochemistry, is the co-author of “Mechanism of Cadmium-mediated Inhibition of Msh2-Msh6 Function in DNA Mismatch Repair,” published in Biochemistry, March 25, 2009. Three undergraduates from three countries worked on the project in the Hingorani Lab at Wesleyan. They include Francis Noah Biro ’09; Markus Wieland, an exchange student from University of Konstanz; and Karan Hingorani, Manju Hingorani’s nephew from St. Xaviers College in Mumbai who did volunteer work in the lab. The project focused on how the heavy metal toxin Cadmium (found in cigarette smoke, industrial pollution, batteries, etc.) causes DNA damage and blocks DNA repair, which promotes development of cancer.
Hingorani also co-authored the article “Mechanism of ATP-Driven PCNA Clamp Loading by S. cerevisiae RFC,” published in the Journal of Molecular Biology, March 13, 2009.
Kit Reed, resident writer in the English Department, is the author of Enclave, published by TOR Books on Feb. 3. In this gripping dystopian satire, ex-marine Sargent Whitmore has a plan to make millions while protecting children from the self-destructing modern world. He turns an old Mediterranean monastery into a combined impenetrable fortress and school, and enrolls 100 filthy-rich children, most of them already well-known for legal troubles, drug problems and paparazzi run-ins. Once there, everyone is cut off from the outside world, fed only canned news stories about wars and natural disasters. When things inevitably go horribly wrong, young hacker “Killer” Stade, physician assistant Cassie, drug and sex-crazed Sylvie and monastery-raised orphan Benny all attempt heroics, but remain deeply flawed. Reed displays unflinching willingness to explore all the facets of all of the characters, and her refusal to paint anyone as a simple villain makes this far more than a typical disaster novel.
Reed speaks about her book in an online interview here.
Mary-Jane Rubenstein, assistant professor of religion, assistant professor of feminist, gender and sexuality studies, is the author of the book, Strange Wonder: The Closure of Metaphysics and the Opening of Awe, published by Columbia University Press, March 2009. Strange Wonder confronts Western philosophy’s ambivalent relationship to the Platonic “wonder” that reveals the strangeness of the everyday. On the one hand, this wonder is said to be the origin of all philosophy. On the other hand, it is associated with a kind of ignorance that ought to be extinguished as swiftly as possible. By endeavoring to resolve wonder’s indeterminacy into certainty and calculability, philosophy paradoxically secures itself at the expense of its own condition of possibility.
Chisel of Remembrance by Vera Schwarcz.
Vera Schwarcz, the Mansfield Freeman Professor of East Asian Studies, chair of the East Asian Studies Proggram, professor of history, professor of East Asian studies, is the author of Chisel of Remembrance, a new collection of poems that draws from roots in Jewish, Chinese, and other ancient traditions. The 76-page book of poetry was published from Antrim House Books.
When parasites attack woolly bear caterpillars, such as this Grammia incorrupta, the insects eat leaves loaded with chemicals called alkaloids, which seems to cure the infection. The discovery, by Michael Singer, represents the first clear demonstration of self-medication among bugs.
Michael Singer, assistant professor of biology, is the author of “Self-Medication as Adaptive Plasticity: Increased Ingestion of Plant Toxins by Parasitized Caterpillars,” published in PLoS ONE, March 2009. PLoS ONE is an open access, online scientific journal from the Public Library of Science.
This new article rigorously demonstrates that caterpillars can self-medicate, following up on a previous publication in Nature in 2005. This is the first experimental demonstration of self-medication by an invertebrate animal.
This paper also represents the first publication to arise from research funded by a National Science Foundation (NSF) grant awarded to Singer in December 2007. Kevi Mace BA ’07 MA ’08 assisted with the research.
The research also was featured in an article titled “Woolly Bear, Heal Thyself,” published in Discover Magazine online, and in an article titled “Woolly Bear Caterpillars Self-Medicate — A Bug First,” published in National Geographic News. The caterpillars also were mentioned in the March 26, 2009 edition of nature-research-highlights-09.
Neuroscience of Birdsong.
John Kirn, chair and professor of neuroscience and behavior, professor of biology, director of Graduate Studies, is the co-author of a book chapter titled “Regulation and function of neuronal replacement in the avian song system.”
The chapter is published inside the book Neuroscience of Birdsong, released in 2009 by Cambridge University Press.
The book provides a comprehensive summary of birdsong neurobiology, and identifies the common brain mechanisms underlying this achievement in both birds and humans. Written primarily for advanced graduates and researchers, there is an introductory overview covering song learning, the parallels between language and birdsong and the relationship between the brains of birds and mammals; subsequent sections deal with producing, processing, learning and recognizing song, as well as with hormonal and genomic mechanisms.
The book was featured in Science Magazine in February 2009 in an article titled “Neuroscience: Singing in the Brain.”
Masami Imai, assistant professor of economics, assistant professor of East Asian studies, and Richard Grossman, chair and professor of economics, are co-authors of the article, “Japan’s Return to Gold: Turning Points in the Value of the Yen during the 1920s,” published in Explorations in Economic History, 2009.
Francisco Rodríguez, assistant professor of economics, assistant professor of Latin American studies, is the co-author of “Anarchy, State, and Dystopia: Venezuelan Economic Institutions before the Advent of Oil,” published in the Bulletin of Latin American Research 28(1), January 2009, pp. 102-21.
In addition, Rodríguez is the author of two book reviews in the December 2008 edition of the Journal of Economic Literature: “Free Trade Reimagined: The World Division of Labor and the Method of Economics by Roberto Mangabeira Unger,” and “A Year without ‘Made in China’: One Family’s True Life Adventure in the Global Economy by Sara Bongiorni.”
Gary Yohe, the Woodhouse/Sysco Professor of Economics, is the co-author of “Assessing dangerous climate change through an update of the Intergovernmental Panel on Climate Change (IPCC) ‘reasons for concern” published in the Proceedings of the National Academy of Sciences, 2009.
Michael Lovell, the Chester D. Hubbard Professor of Economics and Social Sciences, emeritus, is the author of “Social Security’s Five OASI Inflation Indexing Problems,” published in
Economics: The Open-Access, Open-Assessment E-Journal, Vol. 3, 2009.
Dick Miller, the Woodhouse/Sysco Professor of Economics, emeritus, is the author of “The Weighted Cost of Capital is not Quite Right” and “The Weighted Cost of Capital is Not Quite Right: Reply to M Pierru,” published in the Quarterly Review of Economics and Finance, 2009.
Masami Imai, assistant professor of economics, assistant professor of East Asian studies, is the author of “Political Influence and Declarations of Bank Insolvency in Japan,” published in the Journal of Money Credit, and Banking, 2009.