Olivia DrakeScott Holmes, associate professor of molecular biology and biochemistry, received a $5,125 National Science Foundation Research Experience for Undergraduates supplement to enhance his current grant, which supports research titled, “Epigenetic Silencing of Gene Expression in Saccharomyces Cerevisiae.”
Scott Holmes, associate professor of molecular biology and biochemistry, received a grant worth $374,150 from the National Institutes of Health. The grant will support a study on "Functional interaction of histone H1 with the core nucleosome" until 2015. Several Wesleyan undergraduates conducted experiments crucial for developing this grant proposal, including Samantha Schilit '10, MA '11, who is currently in her first year as a Ph.D. candidate at the Harvard School of Medicine. Histone proteins organize DNA into its basic organizational unit, the chromosome, and have a fundamental influence on the function of DNA. The four core histones assemble into the…
Lauren RubensteinThe Molecular Biology and Biochemistry Department sent three professors and six students to the international 2012 Yeast Genetics & Molecular Biology Meeting held at Princeton University recently, giving Wesleyan the largest per capita representation in the world. Attending from the department were Associate Professor and Chair Michael McAlear and his graduate student, James Arnone; Assistant Professor Amy MacQueen and her graduate students Pritam Mukherjee and Lina Yisehak, and recent alumni Sarah Beatie '12 and Louis Taylor '12; and Associate Professor Scott Holmes and his graduate student, Rebecca Ryznar. All spoke or presented on various aspects of yeast genetics, molecular biology,…
This issue, we ask "5 Questions" of Scott Holmes, associate professor of molecular biology and biochemistry. He received a three-year grant from the National Science Foundation (NSF) to support his research on epigenetic silencing of gene expression. Gene expression refers to the observable characteristics generated on a molecular level by a particular sequence of DNA or gene; epigenetic controls are essential in maintaining the specific patterns of gene expression that distinguish hundreds of distinct cell types in skin, muscles and other types of tissue. Epigenetic mechanisms also explain how humans can have more than 200 distinct cell types. Q: Professor Holmes,…
For the next three years, the National Science Foundation (NSF) will support gene expression research led by Scott Holmes, associate professor of molecular biology and biochemistry. On March 2, the NSF awarded Holmes a $599,832, three-year grant for his studies on "Epigenetic Silencing of Gene Expression in Saccharomyces cerevisiae." Gene expression refers to the observable characteristics generated on a molecular level by a particular sequence of DNA or gene; epigenetic controls are essential in maintaining the specific patterns of gene expression that distinguish hundreds of distinct cell types in skin, muscles and other types of tissue. "I’m thrilled to get…
Scott Holmes, associate professor of molecular biology and biochemistry, received a grant from the National Science Foundation (NSF) on March 2. The three year grant, worth $599,832, will support his studies on “Epigenetic Silencing of Gene Expression in Saccharomyces cerevisiae.” Read more on Holmes's study here.