Tag Archive for Chemistry

Current Research Presented at Biophysics, Chemistry Retreat

Vern Schramm spoke on “Drug Design from Transition State Analysis” during the 12th annual Molecular Biophysics and Biological Chemistry Retreat Sept. 22 in Wadsworth Mansion in Middletown. Schramm is professor and the Ruth Merns Chair in Biochemistry at Yeshiva University’s Albert Einstein College of Medicine. He investigates enzymatic transition state structures, which enable him to develop powerful inhibitors for treatment and prevention of cancer and other diseases.

DNA Studies by Hingorani, Beveridge Published in Journals

Manju Hingorani, associate professor of molecular biology and biochemistry, co-authored a study titled “hMSH2 controls ATP processing by hMSH2-hMSH6,” published in the Journal of Biological Chemistry on Sept. 19. The abstract is online here.

Hingorani co-authored another study with David Beveridge, the Joshua Boger University Professor of the Sciences and Mathematics, professor of chemistry, titled “Allosterism in Muts Proteins: How DNA Mismatch Recognition Signals Repair.” The study was published in the Biophysical Journal in 2011. The abstract is online here.

Bolton Published in Mutation Research

Philip Bolton, professor of chemistry, has published “Complexes of mismatched and complementary DNA with minor groove binders: Structures at nucleotide resolution via an improved hydroxyl radical cleavage methodology” in Mutation Research, 2011. The article is online here.

Beveridge Guest Lectures at Institute in New Delhi

Becky Lee '10 and Professor David Beveridge at the Institute of Technology in New Delhi, India.

David Beveridge, the Joshua Boger University Professor of Natural Sciences and Mathematics, professor of chemistry, was on sabbatical last spring at the Indian Institute of Technology (IIT) in New Delhi, India. He was visiting and working on research projects with Professor B. Jayaram, director of the Supercomputer Center for Bioinformatics, SCFBIO.

Beveridge’s former student, Becky Lee ’10, was spending a year doing research in Jayaram’s SCFBIO research group on a project in computational biophysics.

Beveridge presented one of the thematic lectures on “Dynamic Allosterism” in a lecture series celebrating the 50th anniversary of IIT-Delhi.

NIH Supports Molecular Biophysics, Biological Chemistry Program

David Beveridge, the Joshua Boger University Professor of the Sciences and Mathematics, professor of chemistry, received a five year graduate student training grant from the National Institutes of Heath (NIH) in support of Wesleyan’s interdepartmental program in Molecular Biophysics and Biological Chemistry (MBBC). This program is co-coordinated by Ishita Mukerji, professor of molecular biology and biochemistry, director of graduate studies.

The MBBC Program involves 12 faculty members from chemistry, biology, MB&B and physics departments along with both graduate Ph.D. students and undergraduate certificate students. The grant, worth $662,820, is the latest in a series of awards to this program, which has been supported by the NIH since 1988.

Undergraduates Present Research at Summer Poster Session

More than 80 undergraduates presented recent research at the Wesleyan Summer Research Poster Session July 29 in Exley Science Center. Students majoring in biology, molecular biology and biochemistry, psychology, physics, earth and environmental sciences, chemistry, and other disciplines spent at least 10 weeks this summer working on research projects.

Oscar Takabvirwa '14 presented his research on "Solvation of (the peptide) Melittin Using Molecular Modeling." His advisors are Christina Othon, assistant professor of physics, and David Beveridge, the Joshua Boger University Professor of the Sciences and Mathematics, professor of chemistry. This was a dual project between the Department of Physics and Department of Chemistry.

108 Students Benefit from Hughes Summer Research Program

Hughes Fellow Patrick Sarver '14 is spending his summer working with Michael Calter, associate professor of chemistry. He studies “The Catalytic, Asymmetric ‘Interrupted’ Feist-Benary Reaction."

Through a grant from the Howard Hughes Medical Institute, the Wesleyan Hughes Summer Research Program supports undergraduate education in the life sciences. This summer, Wesleyan is hosting 43 Hughes Fellows and approximately 65 Hughes Associates. Hughes Associates are not funded by Hughes, but they participate in Hughes activities.

The program runs from May 25 to July 29 and is open to freshmen, sophomores and juniors currently enrolled at Wesleyan. Fellows receive a $4,000 stipend and are expected to work full-time on their research.

Wesleyan faculty members serve as mentors in the Hughes Summer Research Program. The Summer Program also includes weekly seminars and workshops, a symposium, various social events, and a closing Poster Session. More information on the Wesleyan Hughes Program is online here.

Below is a video and several photographs of 2011 Summer Hughes Fellows:

Provost Announces New University Professors, Artist-in-Residence, Research Professors

Rob Rosenthal, provost and vice president for academic affairs, the John E. Andrus Professor of Sociology, announced a change of title for several faculty members.

These new titles take effect July 1, 2011.

New University Professors

Ronald Kuivila, University Professor of Music, has been teaching at Wesleyan since 1981. He creates sound installations, performs experimental music, and integrates computer programming with music composition. More than 50 of his sound installations have been exhibited internationally, more than 40 works of his concert music have been given major performances, 12 of his works of music for dance have been performed in dance works by major choreographers including Merce Cunningham, his discography includes 11 recordings,

Taylor Awarded DOE Grant for “Imaging Lignin Degradation”

Erika Taylor, assistant professor of chemistry and environmental studies, has received a $193,809 grant from the U.S. Department of Energy for a project called “Imaging Lignin Degradation.” Taylor will collaborate with colleagues at Penn State University and the University of Tennessee.

Taylor hopes to use fluorescence imaging and isotope trace experiments to develop probes for finding organisms that can break down lignin. She plans to test complex biological samples.

“Think going to the forest and bringing home a bucket of dirt containing small insects and lots of microorganisms and then figuring out which ones can break down lignin. This is related to my own work, where I hope to help turn lignin into a viable carbon source for biofuel production,” Taylor explains.

Beveridge Honored at Biophysics Retreat

David Beveridge, the Joshua Boger University Professor of the Sciences and Mathematics., professor of chemistry, was honored at Wesleyan University’s 11th Annual Molecular Biophysics and Biological Chemistry Retreat Sept. 23. Beveridge came to Wesleyan about 30 years ago to develop a program in molecular biophysics within the Department of Chemistry. He studies how the structure, dynamic and solvation of nucleic acids and proteins influence binding and recognition. Pictured is Wesleyan President Michael Roth with Beveridge at the retreat.