Olivia DrakeMarch 3, 20141min
Rex Pratt, the Beach Professor of Chemistry, professor of chemistry, and chemistry graduate student Liudmila Dzhekieva are the co-authors of “Inhibition of DD-Peptidases by a Specific Trifluoroketone: Crystal Structure of a Complex with the Actinomadura R39 DD-Peptidase” published in Biochemistry 52, 2128 in 2013. Pratt and chemistry graduate students Venkatesh Nemmara and Kinjal Dave are the co-authors of  “The Dual Substrate Specificity of Bacillus subtilis PBP4a” published in Biochemistry 52, 2627 in 2013. Rex Pratt and chemistry graduate student Ronak Tilvawala are the co-authors of  “Covalent Inhibition of a Serine ß-Lactamases by Novel Hydroxamic Acid Derivatives” published in Biochemistry, 52,…

Olivia DrakeOctober 2, 20131min
Albert J. Fry, the E. B. Nye Professor of Chemistry, is the author of four new papers published in 2013. "Ion pairing and association effects between tetraalkylammonium Ions and nitrobenzene redox species: Ion pairing to neutral substances” and " Ion pairing of tetraalkylammonium ions to nitrosobenzene and benzaldehyde redox species: A general binding motif for the interaction of tetraalkylammonium ions with benzenoid species," were published in the March and August editions, respectively, of the Journal of Organic Chemistry. The third, "The 'steric effect' of tetraalkylammonium ions on electrochemically generated anions is not steric" was published in the August edition of Electrochemistry Communications. These are the 7th, 8th,…

Olivia DrakeSeptember 16, 20131min
Erika Taylor, assistant professor of chemistry, assistant professor of environmental studies, and chemistry graduate student Kevin Barry, are the co-authors of an article titled "Characterizing the Promiscuity of LigAB, a Lignin Catabolite Degrading Extradiol Dioxygenase from Sphingomonas paucimobilis SYK-6," published in Biochemistry. This article is part of their effort to enable the utilization of lignin, the world’s second most abundant natural polymer, as a carbon source for the production of bioenergy and chemical feedstocks. An abstract will soon be available online here.

Olivia DrakeSeptember 16, 20131min
Brian Northrop, assistant professor of chemistry, is the author of "Experimental and theoretical studies of selective thiol-ene and thiol-yne click reactions involving N-substituted maleimides," published in The Journal of Organic Chemistry in August 2013. Read an abstract of the paper online here. He's also the author of a paper titled "Discrete, soluble covalent organic boronate ester rectangles" published in Chemical Communications, the journal of the Chemical Society, in July 2013. Read an abstract of the paper online here. Northrop's former students, Rob Stolz BA/MA '13 and Natalia Powers-Riggs '13 co-authored both papers.

Lauren RubensteinSeptember 16, 20131min
Lisa Dierker, professor of psychology, and David Beveridge, professor of chemistry and the Joshua Boger Professor of the Sciences and Mathematics, have received a four-year grant for $599,995 from the National Science Foundation’s Transforming Undergraduate Education in Science, Technology, Engineering and Mathematics (TUES) program. This Phase II grant, awarded in August 2013, will support their work on “Passion-Driven Statistics: A multidisciplinary project-based supportive model for statistical reasoning and application,” which began with the development of the QAC 201 “Applied Data Analysis” course and will soon be implemented at other institutions.

Olivia DrakeJuly 29, 20131min
Four Wesleyan faculty and staff members completed the Litchfield Hills Olympic Triathlon held July 14 in New Hartford, Conn. The triathlon featured a 1.5K swim, a 40K bike course, and a scenic, rural back road 10K run. Wesleyan participants included Mike McAlear, associate professor of molecular biology and biochemistry; Tom DiMauro, analyst programmer in ITS; James Taft, assistant director of technology support services in ITS; and Brian Northrop, assistant professor of chemistry. Northrop came in third place overall.

Lauren RubensteinMarch 11, 20132min
University Professor of Natural Science and Mathematics David Beveridge was one of 33 leading experts in science, engineering and technology recently elected to membership in the Connecticut Academy of Science and Engineering. The new members will be introduced at the Academy's 38th annual meeting and dinner on May 22 at Quinnipiac University in Hamden, Conn. According to the Academy, election is "on the basis of scientific and engineering distinction achieved through significant contributions in theory or applications, as demonstrated by original published books and papers, patents, the pioneering of new and developing fields and innovative products, outstanding leadership of nationally…

Olivia DrakeJuly 9, 20122min
On the morning of June 22, Matt Donahue '14 and and Pik-Tone Fung '14 learned that a Wesleyan chemistry professor had been shot in the basement of Hall-Atwater Laboratory. Public Safety taped off the area around Room 078 and removed the body, leaving behind a blood-stained lab coat, a gun, two shell casings, a hand-written note from "Greg Mulligan," a bloody bullet and an overturned chair. Small pools of blood collected under the victim and blood droplets freckled the nearby lab cabinets and counter. The professor did owe $20,000 to Greg Mulligan. Was he murdered for not returning the money?…

Olivia DrakeMay 27, 20125min
Q: Professor Pringle, you joined Wesleyan's Chemistry Department as an assistant professor in 1968. How have times changed? A: I started here before there were female students. Wesleyan had NO COMPUTER at all, and Ph.D. programs were just starting. At the time, we had 11 faculty in the department: Al Fry, Gill Burford, John Sease, Jose Gomez-Ibanez, Peter Leermakers, Julia Tan, Don Sebera and Larry Faller were here, and two faculty came here when I did--Paul Haake from UCLA and Peter Wharton from Wisconsin. Of this group, Al Fry is the only one still working in the department. The department…

Olivia DrakeMarch 26, 20124min
During extended space travel, astronauts may experience dramatic health consequences, such as anemia, due to reduced gravity and exposure to space radiation. To help combat the adverse effects of space ailments, two scientists at Wesleyan are developing new molecules that enhance cells' ability to tolerate large swings in pressure, fluid redistribution, temperature and radiation exposure. Christina Othon, assistant professor of physics, and Erika Taylor, assistant professor of chemistry, assistant professor of environmental studies, received a $20,000 seed grant from NASA's Biological and Physical Research Enterprise to work on the project titled "Osmoregulation for Microgravity Environments." The scientists are taking inspiration from…

Olivia DrakeMarch 26, 20121min
Philip Bolton, professor of chemistry; Dobroslawa Bialonska, postdoctoral fellow in in chemistry; and chemistry graduate student Kenneth Song are the co-authors of "Complexes of mismatched and complementary DNA with minor groove binders. Structures at nucleotide resolution via an improved hydroxyl radical cleavage methodology," published in Mutation Research, 726(1): pages 47-53, 2011. In this paper, the authors explain how they've developed a protocol to investigate the structures of the complexes of damaged DNA with drug like molecules. Tumor cell lines can replicate faster than normal cells and many also have defective DNA repair pathways. This has lead to the investigation of the inhibition of…