A new article by Visiting Assistant Professor in Computer Science Kelly Thayer and students in her Spring 2017 Scientific Computing class is challenging conventional metrics used in allosteric signaling—the regulation of an enzyme by a binding molecule at a site other than the enzyme's active site. “What’s special about allostery is that a molecule called an allosteric effector binds at one location, and the change happens somewhere else,” Thayer explained. “What we were trying to understand was: How does that signal get across?” (more…)