Janice Naegele, professor of biology, professor of neuroscience and behavior, director of the Center for Faculty Career Development, was awarded a $250,000 grant in September from CURE Epilepsy.org. The grant, which will be given over a period of three years, will fund research examining synaptic function in GABAergic stem cell transplants using optogenics. This technique provides a way to modulate and control the activity of individual neurons in living tissue using discrete delivery of light into the brain or tissue slice. It will be used to investigate how GABAergic stem cell transplants suppress seizures in mice with temporal lobe epilepsy.
The new research effort is a collaboration with Laura Grabel, Lauren B. Dachs Professor of Science and Society, professor of biology; Gloster Aaron, associate professor of biology, associate professor of neuroscience and behavior; as well as neuroscientists at Yale and the Children’s Hospital of Philadelphia.