PhD Candidate Case Speaks on DNA Repair

On March 7, Brandon Case, a PhD candidate in molecular biology and biochemistry, delivered a talk titled "Just Another Day Fixing the Double Helix" as part of the Graduate Speaker Series.

On March 11, Brandon Case, a PhD candidate in molecular biology and biochemistry, delivered a talk titled “Just Another Day Fixing the Double Helix” as part of the Graduate Speaker Series. Case’s advisor is Manju Hingorani, professor of molecular biology and biochemistry, professor of integrative sciences. 

Case explained that some diseases arise from changes in enzyme behavior. "By studying their mechanisms, we better understand the cause of diseases," he said. "In addition, many pharamecutials interact with enzymes. Studying the effect of the drug on the enzyme mechanism can determine how the drug works."

The human genome, which contains genetic information needed to grow and build an organism, is under constant assault by damaging agents from sources such as sunlight, tobacco smoke, and barbecued foods. “Fortunately, we have multiple DNA repair pathways that remove damage lesions and restore genome integrity,” Case explained.

The Graduate Speaker Series events include lunch. The entire Wesleyan community is invited. (Photos by Olivia Drake).

The Graduate Speaker Series events are open to the entire Wesleyan community and include lunch. (Photos by Olivia Drake)