Tag Archive for Cohan

Wesleyan in the News

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NewsWesleyan in the News

1. Hartford Courant: “Jeanine Basinger, the ‘Professor of Hollywood,’ Is Wesleyan University’s Homegrown Screen Legend”

Corwin-Fuller Professor of Film Studies, Emerita Jeanine Basinger, whom this article notes has been dubbed “the professor of Hollywood” and “an iconic figure in American cinema, one of the most beloved and respected film history professors in the history of film studies” by The Hollywood Reporter, is interviewed on the occasion of her 60th year at Wesleyan, and the 50th since she created its film program. She talks about her next book on American film comedy, shares some of her favorite things, and muses on which actress would play her in a movie of her life.

2. Los Angeles Review of Books: “‘We Need More Vigorous Debate’: A Conversation with Michael S. Roth”

Daniel Steinmetz-Jenkins, managing editor of Modern Intellectual History, interviews President Michael Roth in connection with his latest book, Safe Enough Spaces: A Pragmatist’s Approach to Inclusion, Free Speech, and Political Correctness on College Campuses. Roth discusses his career path from intellectual historian to university administrator and professor, and offers his unique perspective on debates surrounding freedom of speech and political correctness.

3. Los Angeles Times: “Kirk Douglas Dead at 103; ‘Spartacus’ Star Helped End Hollywood Blacklist”

Jeanine Basinger, the Corwin-Fuller Professor of Film Studies, Emerita, comments on Kirk Douglas’s legacy following the film icon’s death at 103. Recalling when she first saw him on-screen in the 1940s, she said, “He wasn’t a traditional leading man, really, in looks, and yet he had an unmistakable charisma and power on screen—not just the glamour of the movie star, though he did have that, but real acting chops. So you knew he was going to be a star.” She added, “He was a very modern American antihero type, but he could also play anything, really.”

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Cohan in The Conversation: A Clue to Stopping Coronavirus

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Fred Cohan

Fred Cohan

Wesleyan faculty frequently publish articles based on their scholarship in The Conversation US, a nonprofit news organization with the tagline “Academic rigor, journalistic flair.” In this article, Fred Cohan, professor of biology, Huffington Foundation Professor in the College of the Environment, PhD student Kathleen Sagarin, and Kelly Mei ’20 explain how viruses like coronavirus—and several others over history—spread from animals to humans, what determines the size of the outbreak, and how behavioral modifications and technology can stop the spread.

A clue to stopping coronavirus: Knowing how viruses adapt from animals to humans

As the novel coronavirus death toll mounts, it is natural to worry. How far will this virus travel through humanity, and could another such virus arise seemingly from nowhere?

As microbial ecologists who study the origins of new microbial species, we would like to give some perspective.

As a result of continuing deforestation, “bushmeat” hunting of wild animals and caring for our domestic animals, the novel coronavirus will certainly not be the last deadly virus from wild animals to infect humans. Indeed, wild species of bats and primates abound in viruses closely related to SARS and HIV, respectively. When humans interact with wild animal species, pathogens that are resident in those animals can spill over to humans, sometimes with deadly effects.

No new virus under the Sun?

Most “emergent” viruses that are new to humans are regular inhabitants of other species. In some cases, the animal hosts have reached a peaceful coexistence with their viruses, as in the case of bats. In other cases, the viruses are as deadly in their wild animal hosts as in us, as with chimpanzees and their immunodeficiency viruses. Human activities have increased the rate of spillovers of wild animal viruses into our species, particularly from bats.

Deforestation has brought bats closer to human habitations, resulting in recurrent spread of Ebola from bats to humans in sub-Saharan Africa. The trade in wild animals brought us SARS when bats infected captive civets in a live-animal market with the virus. Most profoundly, hunting chimpanzees in Cameroon brought humans HIV about a century ago, most likely by way of an accident in handling an infected carcass.

Other recent, emergent viruses have come to us from bats by way of our domestic animals. Hendra and Nipah virus spilled over in 1994 from fruit bats, by way of horses and pigs in 1999, respectively. In 2012 the MERS virus jumped to humans from camels, which were originally infected from bats several hundred years ago. Caring for our horses’ and camels’ runny noses was responsible for bringing us Hendra and MERS.

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Wesleyan in the News

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NewsIn this recurring feature in The Wesleyan Connection, we highlight some of the latest news stories about Wesleyan and our alumni.

Wesleyan in the News

  1. CNN: “What the ‘Woke Student’ and the ‘Welfare Queen’ Have in Common”

“Every age seems to need a bogeyman, some negative image against which good people measure themselves,” writes President Michael Roth ’78 in this op-ed. Roth compares today’s bogeyman, the “woke” college student, with those of past eras—the “welfare queen” and “dirty hippie”—and seeks to build understanding and dispel negative misperceptions of activist college students. “The images of the welfare queen and of the woke student are convenient because they provide excuses to not engage with difference, placing certain types of people beyond the pale,” he writes. “These scapegoats are meant to inspire solidarity in a group by providing an object for its hostility (or derision), and educators and civic leaders should not play along.”

2. Los Angeles Times: “Opinion: Our Food Is Tainted with E. Coli, Yet the FDA Is Rolling Back Safety Rules”

As yet another food-borne E. coli outbreak sickens Americans, Fred Cohan, the Huffington Foundation Professor in the College of the Environment and professor of biology, and Isaac Klimasmith ’20, argue in this op-ed that more can and should be done to prevent dangerous contaminations of our food supply. The Food and Drug Administration (FDA) has rolled back rules that “would have required monitoring and treating irrigation water for E. coli,” a major cause of these outbreaks. “We should not be surprised that a regulation-averse administration would disregard the science of food safety, but it is concerning that consumers have become complacent about yearly outbreaks of E. coli contamination and largely silent about the rollback of food safety regulations,” they write.

3. The Washington Post: “What Happens When College Students Discuss Lab Work in Spanish, Philosophy in Chinese or Opera in Italian?”

Stephen Angle, director of the Fries Center for Global Studies, professor of philosophy, and the Mansfield Professor of East Asian Studies, is interviewed about Wesleyan’s efforts to promote language study, including the new Cultures and Languages Across the Curriculum (CLAC) initiative, through which students can study a range of disciplines in other languages. For example, Angle teaches a Mandarin-language section of Classical Chinese Philosophy, a course historically taught in English. Read more about CLAC and Wesleyan’s language instruction here.

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Wesleyan in the News

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In this recurring feature in The Wesleyan Connection, we highlight some of the latest news stories about Wesleyan and our alumni.

Recent Wesleyan News

1. Los Angeles Times: “As the World Warms, Deadly and Disfiguring Tropical Diseases Are Inching Their Way Toward the U.S.”

In this op-ed, Professor of Biology Frederick Cohan and Isaac Klimasmith ’20, both in the College of the Environment, write that infectious disease is a growing threat, resulting from climate change, that humans may find hard to ignore. Cohan is also professor, environmental studies and professor, integrative sciences.

2. Hartford Courant: “Trump’s Immoral Response to Climate Report”

Gary Yohe, the Huffington Foundation Professor of Economics and Environmental Studies, writes in this op-ed that it is “irresponsible” and “immoral” to ignore the findings of a major new report on climate change. Delaying action to mitigate and adapt to climate change will be increasingly damaging and expensive, he writes. Yohe is also professor of economics and professor, environmental studies, and was a reviewer on the new National Climate Assessment. He also recently co-authored an op-ed in HuffPost titled “People Are Already Dying by the Thousands Because We Ignored Earlier Climate Change Warnings.” 

3. National Geographic: “Both of NASA’s Voyager Spacecraft Are Now Interstellar. Where to Next?”

With both of NASA’s twin Voyager spacecraft now having crossed the threshold into interstellar space, Seth Redfield, associate professor and chair of astronomy, comments on what the spacecraft are likely to encounter on their journey. Redfield is also associate professor, integrative sciences, and co-coordinator of Planetary Science.

4. Inside Higher Ed: “Ordinary Education in Extraordinary Times”

President Michael Roth writes in this op-ed that in uncommon times, “traditional educational practices of valuing learning from people different from ourselves have never been more important.”

Recent Alumni News

  1. The Takeaway; WNYC Studios: “Politics with Amy Walter: Pentagon’s First-Ever Audit Exposes Massive Accounting Fraud”

David Lindorff ’71, the investigative journalist who wrote an exclusive on the topic for The Nation, joins Walter’s guests—including Staff Sergeant Patricia King, Ambassador Eric Edelman, and Dr. Isaiah Wilson III, a retired Army colonel and senior lecturer with Yale University’s Jackson Institute for Global Affairs—to discuss military spending and its alignment with the military’s strategic goals.

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Biology Team Samples Drought-Tolerant Bacteria in Death Valley

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Nicole DelGaudio ’18 samples the rhizospheres of a juniper tree at about 7,000 feet above sea level.

Nicole DelGaudio ’18 samples the rhizosphere of a juniper tree.

This spring, a research team from Wesleyan traveled to Death Valley National Park to explore the ways bacteria diversifies in extreme environments.

Death Valley, located about 130 miles west of Las Vegas, is a below-sea-level basin known for being the hottest place on earth and driest place in North America. The average rainfall is less than 2 inches, annually.

“National parks are ideal for research, in general, because the land is protected indefinitely from commercial development,” said team leader Fred Cohan, professor of biology, professor of environmental studies. “Death Valley is a nice model system for exobiology because of its extreme habitat.”

Cohan, along with graduate student Jerry Lee, Bella Wiener ’19 and Nicole DelGaudio ’18, traveled to California May 29 through June 4. During this time, the researchers trekked through miles of parched — and often prickly — landscapes seeking to sample root soil, or rhizosphere, from various plant species, each over a wide range of elevations that differ notably in their temperatures.

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Wesleyan Faculty, Students March for Science

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Professor Laura Grabel, pictured sixth from left, attended the March for Science in New Haven, Conn.

Professor Laura Grabel, pictured sixth from left, attended the March for Science in New Haven, Conn.

Numerous Wesleyan faculty and students in the sciences attended the March for Science in different parts of the state and country on Earth Day, April 22.

Laura Grabel, the Lauren B. Dachs Professor of Science and Society, professor of biology, professor of environmental studies, professor of feminist, gender and sexuality studies, spoke at the New Haven march.

“I decided to march because science is being seriously threatened by the Trump administration,” she explained. “Trump has not filled almost all of the science positions, has no science advisor, and is using little evidence-based thinking in his decision making. Some of his appointments are puzzling and scary. From my perspective as a stem cell scientist, appointing Tom Price, who has consistently opposed embryonic stem cell research, as head of Health and Human Services presents a real danger to the future of this work just as therapies are entering clinical trials.”

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Cohan Elected to Connecticut Academy of Science and Engineering

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Fred Cohan

Fred Cohan

Frederick Cohan, professor of biology, professor of environmental studies, has recently been elected to the Connecticut Academy of Science and Engineering (CASE). Set to be inducted during the 42nd Annual Meeting and Dinner on May 22, 2017, Cohan will join 23 others as “Connecticut’s leading experts in science, technology, and engineering,” and the academy’s newest members during their ceremony at the University of Connecticut.

In line with CASE’s mission to honor those “on the basis of scientific and engineering distinction, achieved through significant contributions in theory or application,” Cohan’s work has led to the “development of a comprehensive new theory for the origin, maintenance, and evolutionary dynamics of bacterial species diversity that integrates ecological and genetic criteria; and to the initiation and co-development of associated software tools, which allow microbiologists to identify distinct bacterial species from DNA sequence data.”

Cohan is a graduate of Stanford University, where he earned a bachelor’s degree in biological sciences in 1975. He went on to earn his PhD in organismic and evolutionary biology from Harvard University in 1982. His professional work takes him across the biological and environmental world, including, but not limited to topics such as microbial ecology, evolutionary theory, origins of bacterial diversity, molecular systematics and gene cluster analysis, horizontal genetic transfer and bacterial transformation.

Cohan Presents Research at Microbial Ecology Symposium

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cohanposter
Frederick Cohan, professor of biology, professor of environmental studies, presented his research poster, “Genetic Sweeps by Whisk Brooms and Garage Brooms — the Role of Ecology” at the 16th annual International Symposium on Microbial Ecology, held Aug. 21-26 in Montreal. Cohan presented his models on the origins of bacterial species, in particular that the rate a bacterial group forms new species is determined by the foods it consumes.

Microbial ecology is the study of microbes in the environment and their interactions with each other.

The International Society for Microbial Ecology is the principle non-profit scientific society for the burgeoning field of microbial ecology and its related disciplines. ISME fosters the exchange of scientific information by organizing international symposia as well as specific workshops, sponsoring publications, and promoting education/research. The society offers financial and travel awards during its symposia and provides services to the scientific as well as the wider community.

Cohan Published in Encyclopedia of Genetics, Genomics Publication

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Fred Cohan, chair and professor of biology, professor of environmental studies, is the co-author of “Species,” published in the Encyclopedia of Genetics, Amsterdam, Elsevier, 2013; “Accuracy and efficiency of algorithms for demarcating bacterial ecotypes from DNA sequence data,” published in BMC Genomics, 2013; and “Speedy speciation in a bacterial microcosm: New species can arise as frequently as adaptations within a species,” published in the ISME Journal’s Advance Online Publication, 2013.

Hingorani Group Publishes 8 Papers on DNA Mismatch Repair

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A research group led by Manju Hingorani, associate professor of molecular biology and biochemistry, has published eight papers in 2011-2012 on the mechanisms of DNA replication and repair proteins, independently and in collaboration with research groups at Wesleyan and other national and international universities.

The papers are:

“Large conformational changes in MutS during DNA scanning, mismatch recognition and repair signaling,” published in The EMBO Journal, 2012 (in press).

“The Variable Sub-domain of Escherichia coli SecA functions to regulate in the SecA ATPase Activity and ADP release,” published in the Journal of Bacteriology, 2012 (March 2 Epub). Don Oliver, the Daniel Ayres Professor of Biology, professor of molecular biology and biochemistry, was the lead investigator and Fred Cohan, professor of biology, professor of environmental studies, was a co-author on this paper.

“Single-molecule multiparameter fluorescence spectroscopy reveals directional MutS binding to mismatched bases in DNA,” published in Nucleic Acids Research, 2012 (Feb, 24 Epub).

“Biochemical analysis of the human mismatch repair proteins hMutSαMSH2G674A-MSH6 and MSH2-MSH6T1219D,” published in the Journal of Biological Chemistry, 2012 (Jan. 25 Epub).

“ATP Binding and Hydrolysis-Driven Rate-Determining Events in the RFC-Catalyzed PCNA Clamp Loading Reaction,” published in the Journal of Molecular Biology, Feb. 17, 2012; 416(2), pages 176-91.

“A Central Swivel Point in the RFC Clamp Loader Controls PCNA Opening and Loading on DNA,” published in the Journal of Molecular Biology, Feb. 17, 2012; 416(2), pages 163-75.

“Human MSH2 (hMSH2) protein controls ATP processing by hMSH2-hMSH6,” published in the Journal of Biological Chemistry, Nov. 18, 2011; 286(46), pages 40287-95.

“Dynamical allosterism in the mechanism of action of DNA mismatch repair protein MutS,” published in the Biophysical Journal, Oct. 5, 2011;101(7), pages 1730-9. David Beveridge, the Joshua Boger Professor of the Sciences and Mathematics, was the lead investigator on this paper.

5 Questions With . . . Fred Cohan on Moneyball, Biology

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Fred Cohan

This issue, 5 Questions talks about the connections between the Moneyball and biology with Fredrick Cohan, professor of biology.

Q: Fred, you’ve been talking about how the data mining revolution in baseball, championed by the Michael Lewis book Moneyball and the recent movie of the same name starring Brad Pitt, can change science in general and biology, specifically. Really?

A: Absolutely! On the surface, Moneyball is the story of Billy Beane, the general manager of the Oakland A’s, who found a way to lead his poverty-stricken team to success against teams with many times the payroll of Oakland. But Moneyball is really about the thrill and triumph of data mining—how old data can be gleaned for meaning in ways that were never intended when the data were originally collected. Beane and his colleagues challenged the time-honored “holy trinity” of batting average, home runs, and runs batted in (RBIs) as the essence of a player’s offensive value. They were working off theories developed by Bill James, who posited in the 1970s that these traditional statistics, which everyone in the game knew provided the “truth” about a player’s value, were really imperfect measurements. James mined the data and developed other measurements, such as O.B.P. (on base percentage),

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