Joy Cote PhD ’18, Cody Hecht '18, MA'19, and Erika Taylor, associate professor of chemistry, are the co-authors of a study that explores how opposite charges on our substrate and enzyme cause a protein to change shape when the substrate binds. The study, titled "Opposites Attract: Escherichia coli Heptosyltransferase I Conformational Changes Induced by Interactions between the Substrate and Positively Charged Residues," appears in the February 2020 issue of Biochemistry. "If you can imagine how the opposite charges of magnets are attracted toward each other, then you understand the results of this paper," Taylor explained. "The enzyme uses positively-charged amino…