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Rachel Wachman '24June 18, 20212min
Janice Naegele, Alan M. Dachs Professor of Science, dean of the Natural Sciences and Mathematics Division, and professor of biology, is the co-author of three recent publications. Naegele’s work focuses on stem cells and finding new treatments for epilepsy and brain damage. Naegele’s articles include the following: “Induction of temporal lobe epilepsy in mice with pilocarpine,” published by BioProtocol in February 2020. “Development of electrophysiological and morphological properties of human embryonic stem cell-derived GABAergic interneurons at different times after transplantation into the mouse hippocampus,” published by PLoS One in August 2020. “Optogenetic interrogation of ChR2-expressing GABAergic interneurons after transplantation into…

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Olivia DrakeMarch 23, 20202min
Beginning May 4, 2020, Roger Mathew Grant will succeed Nicole Stanton as Dean of the Arts and Humanities division, and beginning July 1, 2020, Janice Naegele will succeed Joe Knee as Dean of the Natural Sciences and Mathematics division. The announcement was made by Rob Rosenthal, interim provost and senior vice president for academic affairs. Roger Mathew Grant, associate professor of music, received his undergraduate degree from Ithaca College and his PhD from the University of Pennsylvania. In his recent book, Peculiar Attunements: How Affect Theory Turned Musical (Fordham University Press, 2020), he considers contemporary affect theory in relation to European…

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Olivia DrakeApril 9, 20192min
Adult neurogenesis, a process whereby new neurons are added to the brain, is thought to be confined in mammals to just a few regions, including the hippocampus, a structure important for learning. Whether this process occurs in the adult human brain is controversial, but in most other mammals that have been studied, adult neurogenesis in the hippocampus appears to be essential for forming memories. Producing new neurons in the adult hippocampus is regulated by the environment, mood, exercise, diet, and disease. In some forms of epilepsy, the production of new cells in the hippocampus, called granule cells, becomes highly abnormal and…

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Lauren RubensteinMarch 15, 20182min
Wesleyan faculty frequently publish articles based on their scholarship in The Conversation US, a nonprofit news organization with the tagline, “Academic rigor, journalistic flair.” Janice Naegele, the Alan M. Dachs Professor of Science, writes about the implications of a controversial new neuroscience study from the University of California, San Francisco. Naegele also is professor of biology and professor of neuroscience and behavior. Read her bio on The Conversation. Scientists have known for about two decades that some neurons—the fundamental cells in the brain that transmit signals—are generated throughout life. But now a controversial new study from the University of California, San Francisco, casts doubt…

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Olivia DrakeApril 10, 20174min
The Connecticut Technology Council recently selected Professor Janice Naegele as a 2017 "Women of Innovation." Naegele, professor of biology, professor of neuroscience and behavior, was honored during the "Women of Innovation" awards dinner, held March 29 in Plantsville, Conn. The award recognizes women accomplished in science, technology, engineering, math and those who are involved in their community. Naegele is a developmental neuroscientist whose research seeks to identify novel treatments for epilepsy and brain damage. She has published extensively on applications of stem cell transplantation for neural repair, including articles on embryonic stem cell therapy for treating epilepsy and the synaptic mechanisms underlying seizure…

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Lauren RubensteinDecember 12, 20161min
In June, Jan Naegele, professor of biology, professor of neuroscience and behavior, traveled to Mundgod, India to teach Tibetan monks through the Emory-Tibet Science Initiative (ETSI), a program promoting "the convergence of science and spirituality as two complementary systems of knowledge," according to the Emory Tibetan Partnership. ETSI was founded as a pilot in 2006 by Emory University at the bequest of the 14th Dalai Lama. Naegele's journey, which she took together with her husband, Dr. Paul Lombroso, was described in the Winter 2016 issue of Rutland Magazine, in an article featuring many photographs provided by Naegele. (more…)

Lauren RubensteinJune 8, 20162min
Janice Naegele, professor of biology, professor of neuroscience and development, is the co-author of a new paper titled, "Convulsive seizures from experimental focal cortical dysplasia occur independently of cell misplacement." It was published in Nature Communications on June 1. Brain malformations called focal cortical dysplasia are typically formed during human embryonic cortical development and are a common cause of drug-resistant epilepsy and cognitive impairments. One of the causes of cortical dysplasia is improper migration of developing cortical neurons. Failure to reach their correct destinations in the cerebral cortex and dysregulated growth leads to the formation of growths or tubers in regions of…

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Olivia DrakeOctober 21, 20152min
During the Society for Neuroscience's (SfN) annual meeting Oct. 17-21, Janice Naegele, professor of biology, professor of neuroscience and behavior, received the Louise Hansen Marshall Special Recognition Award. The Louise Hanson Marshall Special Recognition Award honors individuals who have significantly promoted the professional development of women in neuroscience through teaching, organizational leadership, public advocacy and more. Naegele shares the 2015 Louise Hansen Marshall award with Paul Greengard P'77, P'79, GP '08, the Vincent Astor Professor at The Rockefeller University in New York. Naegele began her career studying the characteristics of cortical neurons and more recently has performed pioneering studies of transplantation of inhibitory…

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Olivia DrakeOctober 1, 20142min
Jan Naegele, Gloster Aaron and several Wesleyan researchers are the co-authors of an article titled "Long-Term Seizure Suppression and Optogenetic Analyses of Synaptic Connectivity in Epileptic Mice with Hippocampal Grafts of GABAergic Interneurons," published in the October 2014 edition of The Journal of Neuroscience, Issue 34(40): 13492-13504. Naegele is professor of biology, professor of neuroscience and behavior, and director of the Center for Faculty Career Development. Aaron is associate professor of biology, associate professor of neuroscience and behavior. The article is co-authored by Diana Lin '15; graduate students Jyoti Gupta and Meghan Van Zandt; recent alumni Elizabeth Litvina BA/MA '11, XiaoTing Zheng '14, Nicholas Woods '13 and…

Lauren RubensteinOctober 2, 20131min
Janice Naegele, professor of biology, professor of neuroscience and behavior, director of the Center for Faculty Career Development, was awarded a $250,000 grant in September from CURE Epilepsy.org. The grant, which will be given over a period of three years, will fund research examining synaptic function in GABAergic stem cell transplants using optogenics. This technique provides a way to modulate and control the activity of individual neurons in living tissue using discrete delivery of light into the brain or tissue slice. It will be used to investigate how GABAergic stem cell transplants suppress seizures in mice with temporal lobe epilepsy.…

Olivia DrakeMay 26, 20131min
Jan Naegele, professor of biology, professor of neuroscience and behavior, made two presentations in 2013. On March 12, she spoke on "Promises and Pitfalls of Stem Cell Therapy for Brain Disorders" at the 17th Annual Meeting for the Israeli Society for Biological Psychiatry in Kibbutz Hagoshrim, Israel. On March 26, she spoke to the Middlesex Elderly Service Providers on "Stem Cell Therapy for Brain Disorders" in Middletown. On June 11, Naegele will speak on "GABAergic interneuron replacement for temporal lobe epilepsy" at the University of California-Irvine.

Olivia DrakeMay 13, 20133min
Jan Naegele, professor of biology, professor of neuroscience and behavior, was named a 2013-14 ELATE (Executive Leadership in Academic Technology and Engineering) at Drexel® Fellow for the 2013-14 academic year. Naegele and 18 other women faculty in science, technology, engineering and math fields, received the fellowship. They come from a range of universities and colleges across the country, many with global experience. The ELATE at Drexel® Fellow program focuses on increasing personal and professional leadership effectiveness, leading and managing change initiatives within their institutions, using strategic finance and resource management to enhance the missions of their organizations, and creating a…