Naegele

Janice Naegele, Alan M. Dachs Professor of Science, dean of the Natural Sciences and Mathematics Division, and professor of biology, is the co-author of three recent publications. Naegele’s work focuses on stem cells and finding new treatments for epilepsy and brain damage. Naegele’s articles include the following: “Induction of temporal lobe epilepsy in mice with pilocarpine,” published by BioProtocol in February 2020. “Development of electrophysiological and morphological properties of human embryonic stem cell-derived GABAergic interneurons at different times after transplantation into the mouse hippocampus,” published by PLoS One in August 2020. “Optogenetic interrogation of ChR2-expressing GABAergic interneurons after transplantation into…

Beginning May 4, 2020, Roger Mathew Grant will succeed Nicole Stanton as Dean of the Arts and Humanities division, and beginning July 1, 2020, Janice Naegele will succeed Joe Knee as Dean of the Natural Sciences and Mathematics division. The announcement was made by Rob Rosenthal, interim provost and senior vice president for academic affairs. Roger Mathew Grant, associate professor of music, received his undergraduate degree from Ithaca College and his PhD from the University of Pennsylvania. In his recent book, Peculiar Attunements: How Affect Theory Turned Musical (Fordham University Press, 2020), he considers contemporary affect theory in relation to European…

Adult neurogenesis, a process whereby new neurons are added to the brain, is thought to be confined in mammals to just a few regions, including the hippocampus, a structure important for learning. Whether this process occurs in the adult human brain is controversial, but in most other mammals that have been studied, adult neurogenesis in the hippocampus appears to be essential for forming memories. Producing new neurons in the adult hippocampus is regulated by the environment, mood, exercise, diet, and disease. In some forms of epilepsy, the production of new cells in the hippocampus, called granule cells, becomes highly abnormal and…

Wesleyan faculty frequently publish articles based on their scholarship in The Conversation US, a nonprofit news organization with the tagline, “Academic rigor, journalistic flair.” Janice Naegele, the Alan M. Dachs Professor of Science, writes about the implications of a controversial new neuroscience study from the University of California, San Francisco. Naegele also is professor of biology and professor of neuroscience and behavior. Read her bio on The Conversation. Scientists have known for about two decades that some neurons—the fundamental cells in the brain that transmit signals—are generated throughout life. But now a controversial new study from the University of California, San Francisco, casts doubt…

The annual StemCONN conference, held April 27 in New Haven, made clear that Connecticut’s commitment to stem cell research has helped the state become a national leader in this burgeoning area of research and commercial development. Wesleyan is one of the founders of the StemCONN conference, along with Yale and the University of Connecticut. This year marks the 6th StemCONN conference, an event that brings together more than 500 individuals from academic institutions, bioscience industry, and government. “Stem cell research continues to be an exciting and fast-paced field with new discoveries fueling prospects for new therapies based on regenerative medicine…

The Connecticut Technology Council recently selected Professor Janice Naegele as a 2017 "Women of Innovation." Naegele, professor of biology, professor of neuroscience and behavior, was honored during the "Women of Innovation" awards dinner, held March 29 in Plantsville, Conn. The award recognizes women accomplished in science, technology, engineering, math and those who are involved in their community. Naegele is a developmental neuroscientist whose research seeks to identify novel treatments for epilepsy and brain damage. She has published extensively on applications of stem cell transplantation for neural repair, including articles on embryonic stem cell therapy for treating epilepsy and the synaptic mechanisms underlying seizure…

In June, Jan Naegele, professor of biology, professor of neuroscience and behavior, traveled to Mundgod, India to teach Tibetan monks through the Emory-Tibet Science Initiative (ETSI), a program promoting "the convergence of science and spirituality as two complementary systems of knowledge," according to the Emory Tibetan Partnership. ETSI was founded as a pilot in 2006 by Emory University at the bequest of the 14th Dalai Lama. Naegele's journey, which she took together with her husband, Dr. Paul Lombroso, was described in the Winter 2016 issue of Rutland Magazine, in an article featuring many photographs provided by Naegele. (more…)

Janice Naegele, professor of biology, professor of neuroscience and development, is the co-author of a new paper titled, "Convulsive seizures from experimental focal cortical dysplasia occur independently of cell misplacement." It was published in Nature Communications on June 1. Brain malformations called focal cortical dysplasia are typically formed during human embryonic cortical development and are a common cause of drug-resistant epilepsy and cognitive impairments. One of the causes of cortical dysplasia is improper migration of developing cortical neurons. Failure to reach their correct destinations in the cerebral cortex and dysregulated growth leads to the formation of growths or tubers in regions of…

A high school student from New York, who is mentored by a faculty member and a graduate student in Wesleyan's Neuroscience and Behavior Program, is one of the top four finalists for the Neuroscience Research Prize, awarded by the American Academy of Neurology and the Child Neurology Society. As a recipient of the prize, Armonk, N.Y. resident Ryan Infante will receive a $1,000 cash prize and per diem for expenses at the 45th Annual Meeting of the Child Neurology Society in Vancouver, B.C. in October 2016. He will present his stem cell transplantation research during the Child Neurology Society meeting. Infante,…

During the Society for Neuroscience's (SfN) annual meeting Oct. 17-21, Janice Naegele, professor of biology, professor of neuroscience and behavior, received the Louise Hansen Marshall Special Recognition Award. The Louise Hanson Marshall Special Recognition Award honors individuals who have significantly promoted the professional development of women in neuroscience through teaching, organizational leadership, public advocacy and more. Naegele shares the 2015 Louise Hansen Marshall award with Paul Greengard P'77, P'79, GP '08, the Vincent Astor Professor at The Rockefeller University in New York. Naegele began her career studying the characteristics of cortical neurons and more recently has performed pioneering studies of transplantation of inhibitory…

Wesleyan faculty members played key roles in StemCONN 2015, Connecticut's stem cell and regenerative medicine conference, held April 27 in Hartford, Conn. Janice Naegele, professor of biology, professor of neuroscience and behavior, director of the Center for Faculty Career Development, served on the conference's organizing committee for the second time this year. Gloster Aaron, associate professor of biology, associate professor of neuroscience and behavior, spoke at the conference on "Investigating how transplants reduce seizures: brain slice electrophysiology and ontogenetic stimulation of transplanted cells." He discussed the collaborative work being done by his lab and those of Naegele and Laura Grabel, the Lauren B. Dachs…

Eighteen Wesleyan students, research assistants, alumni and one professor attended the Society for Neuroscience's annual meeting, held Nov. 15-19 in Washington D.C. The student group included Wesleyan lab technicians/research assistants Felicia Harrsch and Adam Lombroso and biology graduate students Kemal Asik, Jyoti Gupta, Swechhya Shrestha, Chris Chen, Nickesha Anderson, Meghan van Zandt, Chelsea Lassiter, Samantha Maisel, Julian Gal and Chris Suriano. The alumni group included XiaoTing Zheng '14, Eniola Yeates '10, Efrain Ribiero '10, Michaela Tolman '13 and lab tech/research assistant Katharine Henderson. Most of these alumni are enrolled in Ph.D. or MD/Ph.D neuroscience programs at other universities. Jan Naegele, professor of biology, professor of neuroscience…

Naegele’s Neuroscience Research Published in Journals

Grant, Naegele to Lead Arts and Humanities, Natural Sciences and Mathematics as New Deans

Naegele Lab Releases New Study on Temporal Lobe Epilepsy

Naegele in The Conversation: Are Neurons Added to the Human Brain after Birth?

StemCONN Symposium Shows Connecticut is Leader in Stem Cell Research

Naegele Named a 2017 ‘Women of Innovation’ by the Connecticut Technology Council

Naegele Teaches Neuroscience to Tibetan Buddhist Monks

Naegele Co-Authors New Paper in Nature Communications

High School Student, Mentored by Wesleyan Neuroscience Program, Finalist for Research Prize

Naegele Honored by Society for Neuroscience

Wesleyan Faculty Organize, Speak at StemCONN 2015

Students, Alumni Attend Neuroscience Meeting, Reunion Dinner